RE: "Should we discount the laboratory origin of COVID-19?"

Posted by Krav Maga (A) on June 9, 2021 at 21:48:53

In Reply to: "Should we discount the laboratory origin of COVID-19?" posted by tweaker456 on June 8, 2021 at 17:29:28:

From the "Conclusion" section in the referenced article:

[Edit: At least, Read the first and last sentences in the following quoted material from the article.]

"More than a year after the initial documented cases in Wuhan, the source of SARS-CoV-2 has yet to be identified, and the search for a direct or intermediate host in nature has been so far unsuccessful. The low binding affinity of SARS-CoV-2 to bat ACE2 studied to date does not support Chiroptera as a direct zoonotic agent. Furthermore, the reliance on pangolin coronavirus receptor binding domain (RBD) similarity to SARS-CoV-2 as evidence for natural zoonotic spillover is flawed, as pangolins are unlikely to play a role in SARS-CoV-2′s origin and recombination is not supported by recent analysis.
...

The combination of binding strength, human and mouse peptide mimicry, as well as high adaptation for human infection and transmission from the earliest strains might suggest the use of humanized mice for the development of SARS-CoV-2 in a laboratory environment. The application of mouse strains expressing human ACE2 for SARS-CoV-related research is well documented (Ren et al. 2008; Hou et al. 2010; Menachery et al. 2015; Cockrell et al. 2018; Jiang et al. 2020). Additionally, culturing and adapting coronaviruses to different cell lines, including human airway epithelial cells, has been experimentally conducted in various laboratories (Tse et al. 2014; Menachery et al. 2015; Zeng et al. 2016; Jiang et al. 2020). While a natural origin is still possible and the search for a potential host in nature should continue, the amount of peculiar genetic features identified in SARS-CoV-2's genome does not rule out a possible gain-of-function origin, which should be therefore discussed in an open scientific debate."

Chiroptera refers to bats.
"All thoughts are prey to some beast" - Bill Callahan

"I'll be your mirror
Reflect what you are" - Lou Reed

"Blind belief in authority is the greatest enemy of truth." - Albert Einstein

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Follow Ups Full Thread

Topic - "Should we discount the laboratory origin of COVID-19?" - tweaker456 17:29:28 06/8/21 (27)

RE: "Should we discount the laboratory origin of COVID-19?" - Krav Maga 06/9/2121:48:53 06/9/21 (0)

RE: "Should we discount the laboratory origin of COVID-19?" - pictureguy 19:19:15 06/9/21 (9)

RE: Yo pg,this is right up your ally - tweaker456 21:25:56 06/9/21 (8)

RE: Yo pg,this is right up your ally - pictureguy 22:21:54 06/9/21 (7)

RE: Yo pg,this is right up your ally - tweaker456 09:29:58 06/10/21 (6)

RE: Yo pg,this is right up your ally - pictureguy 12:17:53 06/10/21 (5)

RE: Yo pg,this is right up your ally - tweaker456 15:38:46 06/10/21 (4)

RE: Yo pg,this is right up your ally - pictureguy 16:11:17 06/10/21 (3)

RE: Yo pg,this is right up your ally - tweaker456 17:34:08 06/10/21 (2)

RE: Yo pg,this is right up your ally - pictureguy 17:47:05 06/10/21 (1)

RE: Yo pg,this is right up your ally - tweaker456 20:49:05 06/10/21 (0)

Add this to your reading list... - dark_dave56 04:29:42 06/9/21 (5)

RE: Add this to your reading list... - b.l.zeebub 07:15:56 06/9/21 (3)

Labs collaborate--researchers collaborate... - dark_dave56 07:22:22 06/9/21 (2)

RE: Labs collaborate--researchers collaborate... - b.l.zeebub 08:29:39 06/9/21 (1)

RE: Labs collaborate--researchers collaborate... - dark_dave56 08:43:46 06/9/21 (0)

And another one... - dark_dave56 04:39:45 06/9/21 (0)

Search keywords 'China liability COVID WTO' - Jay Buridan 21:20:17 06/8/21 (5)

RE: Search keywords 'China liability COVID WTO' - tweaker456 22:26:50 06/8/21 (4)

Chinese global assets and accounts can be frozen - Jay Buridan 23:31:52 06/8/21 (3)

But they won't be... - Steve O 05:53:07 06/9/21 (2)

I hope you're wrong Steve - Jay Buridan 06:19:33 06/9/21 (1)

RE: I hope you're wrong Steve - tweaker456 09:04:59 06/9/21 (0)

No (mt) - Goober58 19:46:53 06/8/21 (0)

RE: "Should we discount the laboratory origin of COVID-19?" - Mike_in_MD 17:47:55 06/8/21 (0)

RE: "Should we discount the laboratory origin of COVID-19?" - jedrider 17:45:25 06/8/21 (1)

Exactly... - Ivan303 18:10:49 06/8/21 (0)

Follow Ups

RE: "Should we discount the laboratory origin of COVID-19?" - Krav Maga 06/9/2121:48:53 06/9/21 (0)

RE: "Should we discount the laboratory origin of COVID-19?"

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